Diabetes is a syndrome characterized by metabolic chronic disorder that is companied by an increase in the level of blood sugar above the normal level as a result of the inability of the pancreatic beta cells to secrete insulin partially or completely or lower the tissues' sensitivity to insulin, and therefore, the cell did not get any benefit from this hormone. Diabetes is one of the most common chronic diseases across the world, and the World Health Organization (WHO) predicts that by 2025 there will be nearly 300 million cases. Currently, medicinal plants receive an interest in the treatment of many diseases or reduce their complication. Tea is the second most popular drink in the world after water, and many studies highlighted the effects of the drink tea. Therefore, the aim of this study was to explore the effects of white tea extract on some biochemical parameters on the diabetic rats induced by streptozotocin (STZ). In the present study, rat serum and liver tissues were used for the determination of the concentrations of glucose, lipid profile, which includes the cholesterol, triglyceride (TG), high-density lipoproteins (HDL-C), as well as the antioxidant enzymes activity superoxide dismutase (SOD), glutathione peroxidase (GSH-px) and catalase (CAT). In addition to that, the effect of white tea extract on the gene expression of glucose transporter -2 in both the liver and pancreas tissues was investigated...